Python code to run and train our prediction models is available at the following GitHub repositories:

Enzyme-Substrate Pair Prediction:

• Running the original ESP model:
  https://github.com/AlexanderKroll/ESP_prediction_function
• Reproducing the results of the ESP paper:
  https://github.com/AlexanderKroll/ESP
• Reproducing the results of the ProSmith paper:
  https://github.com/AlexanderKroll/ProSmith

Turnover Number k_cat Prediction:

• Running the trained model:
  https://github.com/AlexanderKroll/kcat_prediction_function
• Reproducing the results of the paper:
  https://github.com/AlexanderKroll/kcat_prediction

Michaelis Constant K_M Prediction:

• Running the trained model:
  https://github.com/AlexanderKroll/KM_prediction_function
• Reproducing the results of the paper:
  https://github.com/AlexanderKroll/KM_prediction

Transporter-Substrate Pair Prediction:

• Reproducing the results of the paper:
  https://github.com/AlexanderKroll/SPOT